K.H.A.I.T.O. is an educational simulation. It is a teaching model of how a drug or a compound might move through the brain, built from published research.
It is not a medical device, not a diagnostic tool and not a clinical decision aid. It is not registered with, approved by or reviewed by the Medical Device Authority of Malaysia, the FDA, the EMA or any other regulator, and no such approval is claimed or implied.
Its predictions are not validated against laboratory or clinical outcomes. They do not describe what a drug, a compound or an exosome preparation will do in any real person. Parts of the model are the author's own estimates, and the software labels those parts wherever they appear.
Do not use it to make any decision about a person's health, a treatment, a dose or an experiment. If you have a medical question, ask a qualified clinician. Nothing here is medical advice.
Every dataset in the model is open-licence. The application itself carries a full "Licences and credits" table naming each source, its licence and whether it allows commercial use. The short version:
| Layer | Source and licence |
|---|---|
| Receptor and transporter density | Human PET studies released under CC0, CC BY or MIT, plus regional values typed from open-access CC BY papers |
| Cortical wiring | MICA-MICs group-average connectome, 50 adults (Royer et al. 2022), CC0 1.0 |
| Autism connectivity | Published direction only, from a CC BY 4.0 paper; the size of the effect is this model's own estimate |
| Disease maps | Cohen's d values read from the published ENIGMA working-group papers and cited as findings |
| Blood–brain barrier | B3DB, CC0 |
| Drug parameters | Regulatory labels and published PET studies, tagged per value |
Several of these sources ask to be cited, and they are cited inside the application. If you think a source is credited wrongly, please get in touch and it will be corrected or removed.
The cortical surface you rotate on screen is derived from the Conte69 group-average surface, which comes from Human Connectome Project open-access data. The HCP's terms let anyone redistribute their data "and any derived data … as long as the data are redistributed under these same Data Use Terms." So that one layer reaches you under the WU-Minn HCP Consortium Open Access Data Use Terms, and by using K.H.A.I.T.O. you agree to them. In plain words: acknowledge the HCP if you present results that relied on it, make no attempt to identify any individual from it, and pass these same terms on if you pass the data on. The HCP acknowledgement is given inside the application.
These apply to anyone who pays for the full version. The free preview needs no key, costs nothing and is covered by the disclaimer above.
K.H.A.I.T.O. is written and sold by its author, an individual based in Malaysia. There is no company behind it yet, and no business registration number to quote; if that changes the details will appear here. Questions, problems and refund requests go through the contact form, and are answered by one person.
A licence key that gives one person access to the full version through this website for the period you paid for. Access runs through the website: there is no installable copy and no source code in the purchase.
The key is yours. Use it on your own devices. Please do not share it, publish it or resell it. A key being used by many people at once may be switched off.
If K.H.A.I.T.O. is not what you expected, ask within 14 days of paying and you get your money back in full. You do not have to give a reason. This is deliberately simple: the software is unusual, and you should be able to change your mind after seeing it.
After 14 days a payment already made is not refundable, but you can stop at any time and nothing further will be taken. Refunds go back by the route you paid.
You can stop whenever you like. If a renewal is involved, cancel before it falls due. Access runs to the end of the period you have already paid for.
Access may be withdrawn, with a refund of the unused part, if a key is shared widely, if the application is used to give anyone medical advice, or if it is copied or resold.
K.H.A.I.T.O. is provided as it is. To the extent the law allows, the author is not liable for any loss, injury, cost or damage arising from a decision taken on the strength of anything this software shows you, and total liability is limited to the amount you paid in the previous twelve months. Nothing here removes a right you have under Malaysian consumer law that cannot be contracted away.
Paying leaves a record of your email address and your payment, kept so that your key can be issued and supported. The payment itself is handled by a payment provider, which has its own terms and privacy policy; card and banking details never reach this website. Your details are not sold and not used for anything else. To have them deleted, ask.
The application runs inside your browser. What you type into it — compounds, doses, conditions — is not sent anywhere and not stored.
These terms are governed by the laws of Malaysia.